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  • Title: Antibasal Ganglia Antibodies and Antistreptolysin O in Noncomorbid ADHD.
    Author: Toto M, Margari F, Simone M, Craig F, Petruzzelli MG, Tafuri S, Margari L.
    Journal: J Atten Disord; 2015 Nov; 19(11):965-70. PubMed ID: 22956712.
    Abstract:
    OBJECTIVE: An association between streptococcal infections, ABGA positivity, and no comorbidity ADHD (nc-ADHD) has been little investigated. The aim of this study was to evaluate the streptococcal infection frequency, defined entitled serum antistreptolysin O (ASO), and frequency of serum ABGA positivity in a sample of patients with nc-ADHD. METHOD: In all 40 participants were investigated the ASO titer and ABGA. RESULTS: The results showed that ABGA positivity was statistically significantly higher in patients affected by ADHD than in patients of a control group, and pathological values of ASO were statistically more frequent in the ADHD group than the control group. CONCLUSION: These data suggest that streptococcal infections and autoimmune reactions against the basal ganglia are more frequent in ADHD patients than patients in a control group.
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