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  • Title: A general intramolecular Friedel-Crafts approach to functionalized pyrrolo[3,2,1-ij]quinolin-4-ones.
    Author: Patil DV, Cavitt MA, Grzybowski P, France S.
    Journal: Chem Commun (Camb); 2012 Oct 25; 48(83):10337-9. PubMed ID: 22968155.
    Abstract:
    An indium(III)-catalyzed intramolecular Friedel-Crafts annulation for the efficient synthesis of pyrrolo[3,2,1-ij]quinolin-4-ones is described. The products are formed in good to excellent yields (51-97%) with diastereoselectivities up to >99 : 1 dr.
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