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  • Title: Skeletal complications of bisphosphonate use: what the radiologist should know.
    Author: Haworth AE, Webb J.
    Journal: Br J Radiol; 2012 Oct; 85(1018):1333-42. PubMed ID: 22972971.
    Abstract:
    Bisphosphonates are widely used for prevention of fractures in patients at risk, mainly in the presence of osteoporosis and bone metastases. A number of adverse effects of prolonged bisphosphonate treatment have emerged. We would like to highlight the skeletal complications from which a radiologist may be the first healthcare professional to recognise the association with bisphosphonate therapy. We illustrate these complications (namely osteonecrosis of the jaw and less well-known atypical femoral shaft fractures), presenting radiological findings in our patients. Recommendations for safer use of bisphosphonates are included in the conclusion of our review.
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