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  • Title: Stages of early acute renal dysfunction in liver transplantation: the influence of graft function.
    Author: Umbro I, Rossi M, Tinti F, Fiacco F, Piselli P, Ianni S, Ginanni Corradini S, Poli L, Berloco PB, Mitterhofer AP.
    Journal: Transplant Proc; 2012 Sep; 44(7):1953-5. PubMed ID: 22974880.
    Abstract:
    The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function.
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