These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Nightshift work job exposure matrices and urinary 6-sulfatoxymelatonin levels among healthy Chinese women.
    Author: Ji BT, Gao YT, Shu XO, Yang G, Yu K, Xue SZ, Li HL, Liao LM, Blair A, Rothman N, Zheng W, Chow WH.
    Journal: Scand J Work Environ Health; 2012 Nov; 38(6):553-9. PubMed ID: 22975884.
    Abstract:
    OBJECTIVE: Six-sulfatoxymelatonin (aMT6s) is a primary urinary metabolite of melatonin. We examined the association between aMT6s levels and shift work estimated by a job exposure matrix (JEM) among healthy participants of the Shanghai Women's Health Study. METHODS: Creatinine-adjusted aMT6s levels were measured in the urine samples of 300 women and related to JEM shift work categories. RESULTS: Adjusted geometric means of aMT6s levels from urine samples collected before 08:00 hours were lower among persons holding nighttime shift work jobs. The adjusted aMT6s levels (ng/mg creatinine) were 8.36 [95% confidence intervals (95% CI) 4.47-15.6], 6.37 (95% CI 3.53-11.5), 6.20 (95% CI 3.33-11.5), 3.81 (95% CI 2.02-7.19), and 3.70 (95% CI 1.92-7.11) from the lowest (never held a shift work job) to the highest (current job likely involved all-night shift work) shift work JEM scores (P=0.05). CONCLUSION: Our results indicate that nightshift work JEM scores were significantly and inversely associated with aMT6s levels in early morning spot urine samples collected between 07:00-08:00 hours.
    [Abstract] [Full Text] [Related] [New Search]