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  • Title: Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities.
    Author: Zhang M, Wang JS, Wang PR, Oyama M, Luo J, Ito T, Iinuma M, Kong LY.
    Journal: Fitoterapia; 2012 Dec; 83(8):1604-9. PubMed ID: 22986292.
    Abstract:
    Four new sesquiterpenes, chlorajapolides F-I (1-4), along with nine known terpenoids (5-13) were isolated from the aerial part of Chloranthus japonicus. Their structures were elucidated on the basis of spectroscopic analysis, and a lindenane sesquiterpene, named 9-hydroxy-heterogorgiolide, previously isolated from the C. japonicus, was revised as its 8-epimer (1a). Moreover, methanol extract (ME), EtOAc fraction (EF), water fraction (WF), and all isolates (1a, 1-13) were evaluated for their cytotoxicities using two human cancer cell lines.
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