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  • Title: Focal high-concentration trichloroacetic acid peeling for treatment of atrophic facial chickenpox scar: an open-label study.
    Author: Barikbin B, Saadat N, Akbari Z, Yousefi M, Toossi P.
    Journal: Dermatol Surg; 2012 Oct; 38(10):1662-7. PubMed ID: 22989024.
    Abstract:
    BACKGROUND: Despite their prevalence, there is a paucity of information in the medical literature on the treatment of atrophic chickenpox scars. OBJECTIVE: To evaluate the efficacy and safety of using the chemical reconstruction of skin scar technique for the treatment of atrophic facial chickenpox scars. METHODS AND MATERIALS: One hundred patients (mean age 23 years; Fitzpatrick skin types II-IV) were treated with focal chemical peeling with 70% trichloroacetic acid (TCA) for a maximum of six sessions. Improvement rate, frequency of adverse events and patient satisfaction were assessed. RESULTS: Five hundred thirty-three peeling sessions in 100 consecutive patients were performed. Final assessment at 12-week follow-up visit after the last treatment revealed improvement in 95% of patients: mild improvement in 12 cases, moderate improvement in 42 cases, and marked improvement in 41 cases. The appearance of scars did not change in five patients. Seventy-nine patients expressed moderate to high satisfaction with the results. Post-treatment side effects were mild and transient, resolving gradually within the study period. CONCLUSION: Focal peeling with high-concentration TCA appears to be a safe and effective alternative in the treatment of atrophic facial chickenpox scars.
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