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  • Title: Masking procedure, randomization and stratification, and compliance monitoring in the Growth Failure in Children with Renal Diseases Study.
    Author: Shasky DA, Coppedge SH, Boyle RM, Chan JC.
    Journal: J Pediatr; 1990 Feb; 116(2):S22-3. PubMed ID: 2299482.
    Abstract:
    Ensuring the integrity of a study such as the GFRD Study requires close cooperation among all groups involved with the study and the patient. Many factors may influence the outcome and validity of a multicenter, double-masked, randomized trial. Any dosage modifications that may need to be made rely totally on established communication between the centers, the DCC, and the Core Pharmacy. When the procedures outlined above are followed, masking is ensured and patient compliance can be measured.
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