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  • Title: In vitro Etest synergy of doripenem with amikacin, colistin, and levofloxacin against Pseudomonas aeruginosa with defined carbapenem resistance mechanisms as determined by the Etest method.
    Author: He W, Kaniga K, Lynch AS, Flamm RK, Davies TA.
    Journal: Diagn Microbiol Infect Dis; 2012 Dec; 74(4):417-9. PubMed ID: 22995366.
    Abstract:
    The applicability of Etest for synergy testing was evaluated in 100 carbapenem-nonsusceptible Pseudomonas aeruginosa isolates. Combinations of doripenem with amikacin, colistin, or levofloxacin were synergistic or additive against 67%, 31%, and 23% of isolates, respectively. The use of Etest was practical to evaluate the synergy of doripenem with other antipseudomonal agents.
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