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  • Title: Streptococcus agalactiae infective endocarditis with large vegetation in a patient with underlying protein S deficiency.
    Author: Cheng HL, Lin WC, Shih PY, Huang CH, Hsu YC, Yie JC, Chen SY, Lin CP.
    Journal: Infection; 2013 Feb; 41(1):247-50. PubMed ID: 23001489.
    Abstract:
    We present a case of a patient with underlying protein S deficiency who suffered from infective endocarditis with a large anterior mitral leaflet (AML) mass of approximately 4.5 cm in length. Intraoperative transesophageal echocardiography (TEE) revealed the mass at the AML base and a rupture of the posterior mitral leaflet chordae tendinae. The vegetation's large size may have been caused by one or more of three factors: location, underlying disease, and the microorganism causing infection. Patients with protein S deficiency are prone to thromboembolic events during cardiac surgery. Infective endocarditis caused by Streptococcus agalactiae usually has a poor prognosis, and, thus, early surgery is recommended.
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