These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Organization and evolution of synthetic idiotypic networks.
    Author: Agliari E, Asti L, Barra A, Ferrucci L.
    Journal: Phys Rev E Stat Nonlin Soft Matter Phys; 2012 May; 85(5 Pt 1):051909. PubMed ID: 23004790.
    Abstract:
    We introduce a class of weighted graphs whose properties are meant to mimic the topological features of idiotypic networks, namely, the interaction networks involving the B core of the immune system. Each node is endowed with a bit string representing the idiotypic specificity of the corresponding B cell, and the proper distance between any couple of bit strings provides the coupling strength between the two nodes. We show that a biased distribution of the entries in bit strings can yield fringes in the (weighted) degree distribution, small-world features, and scaling laws, in agreement with experimental findings. We also investigate the role of aging, thought of as a progressive increase in the degree of bias in bit strings, and we show that it can possibly induce mild percolation phenomena, which are investigated too.
    [Abstract] [Full Text] [Related] [New Search]