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  • Title: Myoepithelial carcinoma of the retromolar area with extensive mandibular involvement.
    Author: Pontes HA, Pontes FS, Toral-Rizo V, de Andrade BA, Fonseca FP, de Almeida OP.
    Journal: J Cutan Pathol; 2012 Dec; 39(12):1135-43. PubMed ID: 23005699.
    Abstract:
    Myoepithelial tumors were first described in 1943, and account for less than 1% of all salivary gland neoplasms. Their malignant variant, myoepithelial carcinoma, was first reported by Stromeyer et al. in 1975 and represents a very rare entity, characterized by distinct morphologic heterogeneity and an infiltrative growth pattern into adjacent tissues. However, there have been few reports on myoepithelial carcinoma affecting intra-oral minor salivary glands, and its immunohistochemical features have been poorly illustrated. We herein describe a rare case of myoepithelial carcinoma affecting the retromolar region of a 52-year-old woman that caused extensive mandibular bone destruction. We also reviewed the English literature concerning the involvement of intra-oral minor salivary glands by myoepithelial carcinoma.
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