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  • Title: Rhabdomyolysis associated with influenza A/H1N1 2009 infection in a pediatric patient.
    Author: Ishiwada N, Takada N, Okunushi T, Hishiki H, Katano H, Nakajima N, Kohno Y.
    Journal: Pediatr Int; 2012 Oct; 54(5):703-5. PubMed ID: 23005902.
    Abstract:
    The influenza A/H1N1 2009 epidemic has spread to many countries since 2009, including Japan. We report an immune-competent child involving rhabdomyolysis and compartment syndrome associated with influenza A/H1N1 2009. The patient was demonstrated rhabdomyolysis with myoglobinuria, hyperkalemia, cardiac dysfunction and compartment syndrome that arose during convalescence from influenza A/H1N1 2009 infection. Although RT-PCR of muscle tissue yielded negative results for influenza A/H1N1 2009 RNA and no viral positive-antigen cells were detected in the muscle lesions, the clinical picture suggested rhabdomyolysis associated with influenza A/H1N1. Rhabdomyolysis should be considered in the evaluation of muscle symptoms such as myalgia associated with novel influenza A/H1N1 2009 virus infection, particularly in critically ill patients.
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