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  • Title: Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents.
    Author: Lucas SJ, Lord RM, Wilson RL, Phillips RM, Sridharan V, McGowan PC.
    Journal: Dalton Trans; 2012 Dec 07; 41(45):13800-2. PubMed ID: 23015068.
    Abstract:
    Several Ru-arene and Ir-Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.
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