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  • Title: Oral Candida colonization and candidiasis in patients with psoriasis.
    Author: Bedair AA, Darwazeh AM, Al-Aboosi MM.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol; 2012 Nov; 114(5):610-5. PubMed ID: 23022022.
    Abstract:
    OBJECTIVES: The objective of this study was to investigate oral Candida colonization and candidosis in a group of patients with psoriasis and controls. STUDY DESIGN: A total of 100 patients with psoriasis and matched controls underwent the concentrated oral rinse test for Candida isolation. Candida species were identified by the VITEK 2 Identification System. Categorical variables were evaluated using the χ(2) test. The median Candida count was compared using the Mann-Whitney U test. RESULTS: Oral candidiasis was diagnosed in 3% of the patients with psoriasis. The Candida count and prevalence were significantly higher in the patients with psoriasis compared with controls (69% vs 44%, P < .001), but with no relationship to the severity or treatment of psoriasis. Oral Candida was significantly higher in late-onset (at age ≥30 years) compared with early-onset psoriasis (at age <30 years). CONCLUSIONS: Patients with psoriasis have increased oral Candida colonization and candidiasis. Further studies are needed to clarify the predisposing factor(s) for oral Candida in patients with psoriasis.
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