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  • Title: Toxic megacolon associated with cytomegalovirus infection in a patient with steroid-naïve ulcerative colitis.
    Author: Inoue K, Wakabayashi N, Fukumoto K, Yamada S, Bito N, Yoshida N, Katada K, Uchiyama K, Ishikawa T, Handa O, Takagi T, Konishi H, Yagi N, Kokura S, Kishimoto M, Yanagisawa A, Naito Y.
    Journal: Intern Med; 2012; 51(19):2739-43. PubMed ID: 23037465.
    Abstract:
    Most cases of cytomegalovirus (CMV) colitis in patients with inflammatory bowel disease (IBD) occur in those treated with immunosuppressants and/or corticosteroids. We herein present the case of a 57-year-old man with toxic megacolon associated with CMV colitis in corticosteroid-naïve ulcerative colitis (UC). To date, there have been only eight previous case reports of CMV colitis in steroid-naïve UC. We discuss the need to consider CMV colitis when making a differential diagnosis of patients with refractory UC who are not receiving corticosteroid treatment.
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