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  • Title: Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs.
    Author: Salvador JA, Moreira VM, Gonçalves BM, Leal AS, Jing Y.
    Journal: Nat Prod Rep; 2012 Dec; 29(12):1463-79. PubMed ID: 23047641.
    Abstract:
    This review highlights the potential of natural and semisynthetic ursane-type triterpenoids as candidates for the design of multi-target bioactive compounds, with focus on their anticancer effects. A brief illustration of the biosynthesis, sources, and general biological effects of the main classes of naturally occurring pentacyclic triterpenoids (PTs) are provided.
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