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  • Title: [Clinical aspects of severe digitalis poisoning and its treatment with and without digoxin-specific antibodies. 3 case reports].
    Author: Haefeli WE, Ritz RF.
    Journal: Schweiz Med Wochenschr; 1990 Feb 10; 120(6):155-8. PubMed ID: 2305225.
    Abstract:
    Although elevated digitalis concentrations are often observed, symptomatic intoxications occur less frequently. We report the course in three patients with extremely elevated digitalis concentrations as examples of the poor correlation between measured serum levels and symptoms. In view of the cost of treatment by fab-fragments and the lack of a close dose-related effect of digitalis, we suggest restricting the use of fab-fragment therapy to patients with severe hyperkalemia or hemodynamically relevant arrhythmias.
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