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  • Title: Marek's disease in chickens: correlation of Marek's disease with nuclear-inclusion formation in feather-follicle epithelium.
    Author: Moriguchi R, Izawa H.
    Journal: Avian Dis; 1979; 23(3):547-54. PubMed ID: 230801.
    Abstract:
    The dynamics of nuclear-inclusion (NI) formation in feather-follicle epithelium of chickens inoculated with Marek's disease virus (with or without prior immunization with turkey herpesvirus) could be divided into two patterns: 1) transient NI formation at the initial stage postchallenge; and 2) persistent NI formation. Incidence of Marek's disease was closely correlated with the dynamics of NI formation. Active NI formation recurred in chickens showing pattern 2 and was closely related to the incidence of nerve lesions.
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