These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [In vitro chemosensitivity test: succinate dehydrogenase inhibition (SDI) test].
    Author: Maehara Y, Kohnoe S, Emi Y, Sakaguchi Y, Sugimachi K.
    Journal: Rinsho Byori; 1990 Jan; 38(1):14-8. PubMed ID: 2308218.
    Abstract:
    The succinate dehydrogenase inhibition (SDI) test was used for determining chemosensitivity of various human tumors. This test was based on the correlation between the cellular succinate dehydrogenase activity as determined by 3-(4,5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2H tetrazolium bromide (MTT), and cell viability. The chemosensitivity varied in the tissue. Some factors are involved in the chemosensitivity, that is origin of a tumor, tissue differentiation and tissue DNA synthetic activity. This test is a convenient method for clinical use and provides important information about chemosensitivity.
    [Abstract] [Full Text] [Related] [New Search]