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  • Title: Decline in macrolide-resistant Streptococcus pyogenes isolates from French children.
    Author: d'Humières C, Cohen R, Levy C, Bidet P, Thollot F, Wollner A, Bingen E.
    Journal: Int J Med Microbiol; 2012 Dec; 302(7-8):300-3. PubMed ID: 23103047.
    Abstract:
    We studied the macrolide resistance and serotypes of 585 group A streptococcus (GAS) isolates collected from French children with pharyngitis. Nineteen isolates (3.2%) were erythromycin-resistant and harbored the following resistance genes: 31.6% mef(A), 15.8% erm(A), and 52.6% erm(B). The 19 isolates included 7 different emm types (4, 1, 11, 2, 28, 12, and 77) and 7 corresponding multilocus sequence types. The current fall in macrolide consumption has led to a very low rate of GAS macrolide resistance.
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