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  • Title: Synthesis of oxazoles from enamides via phenyliodine diacetate-mediated intramolecular oxidative cyclization.
    Author: Zheng Y, Li X, Ren C, Zhang-Negrerie D, Du Y, Zhao K.
    Journal: J Org Chem; 2012 Nov 16; 77(22):10353-61. PubMed ID: 23106159.
    Abstract:
    A group of functionalized oxazoles were synthesized in moderate to good yields from enamides via phenyliodine diacetate (PIDA)-mediated intramolecular cyclization. The main advantageous features of the present method include its broad substrate scope and the heavy-metal-free characteristic of the oxidative carbon-oxygen bond formation process.
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