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  • Title: A highly active catalytic system for Suzuki-Miyaura cross-coupling reactions of aryl and heteroaryl chlorides in water.
    Author: Mao SL, Sun Y, Yu GA, Zhao C, Han ZJ, Yuan J, Zhu X, Yang Q, Liu SH.
    Journal: Org Biomol Chem; 2012 Dec 21; 10(47):9410-7. PubMed ID: 23111458.
    Abstract:
    An easily available Pd(OAc)(2)/(2-mesitylindenyl)dicyclohexylphosphine/Me(octyl)(3)N(+)Cl(-)/K(3)PO(4)·3H(2)O catalytic system was developed and it shows high catalytic activity in the Suzuki-Miyaura cross-coupling reaction of a diverse array of aryl and heteroaryl chlorides in water. Notably, this catalytic system also works with ultra-low loading of the catalyst with high turnover numbers.
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