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  • Title: Synthesis and pharmacological activity of alkaloids from embryo of lotus, Nelumbo nucifera.
    Author: Nishimura K, Horii S, Tanahashi T, Sugimoto Y, Yamada J.
    Journal: Chem Pharm Bull (Tokyo); 2013; 61(1):59-68. PubMed ID: 23117579.
    Abstract:
    Bisbenzylisoquinoline alkaloid, nelumboferine which was recently isolated from the embryo of Nelumbo nucifera, and stereoisomers of neferine, which is a major alkaloid of the embryo of N. nucifera, were stereoselectively synthesized. Pharmacological activity of nelumboferine, stereoisomers of neferine, liensinine, isoliensinine, and O-methylneferine were evaluated.
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