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  • Title: An ocular form of myasthenia gravis with a high titer of anti-MuSK antibodies during a long-term follow-up.
    Author: Hosaka A, Takuma H, Ohta K, Tamaoka A.
    Journal: Intern Med; 2012; 51(21):3077-9. PubMed ID: 23124154.
    Abstract:
    We herein report a case of ocular myasthenia gravis (MG) that was highly positive for anti-muscle-specific tyrosine kinase (MuSK) antibodies. The examined patient exhibited bilateral ptosis and lateral gaze palsy without any generalized symptoms and was diagnosed with ocular MG with anti-MuSK antibodies. She responded to treatment with prednisolone and immunosuppressants and experienced only ocular symptoms for four years and eight months after onset. Ocular MG with anti-MuSK antibodies lasting for a long term has rarely been described. Our findings suggest that it may be reasonable to test for the presence of anti-MuSK antibodies in patients who present with external ophthalmoplegia.
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