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  • Title: Precision of higher-order aberration measurements with a new Placido-disk topographer and Hartmann-Shack wavefront sensor.
    Author: López-Miguel A, Martínez-Almeida L, González-García MJ, Coco-Martín MB, Sobrado-Calvo P, Maldonado MJ.
    Journal: J Cataract Refract Surg; 2013 Feb; 39(2):242-9. PubMed ID: 23142546.
    Abstract:
    PURPOSE: To assess the intrasession and intersession precision of ocular, corneal, and internal higher-order aberrations (HOAs) measured using an integrated topographer and Hartmann-Shack wavefront sensor (Topcon KR-1W) in refractive surgery candidates. SETTING: IOBA-Eye Institute, Valladolid, Spain. DESIGN: Evaluation of diagnostic technology. METHODS: To analyze intrasession repeatability, 1 experienced examiner measured eyes 9 times successively. To study intersession reproducibility, the same clinician obtained measurements from another set of eyes in 2 consecutive sessions 1 week apart. Ocular, corneal, and internal HOAs were obtained. Coma and spherical aberrations, 3rd- and 4th-order aberrations, and total HOAs were calculated for a 6.0 mm pupil diameter. RESULTS: For intrasession repeatability (75 eyes), excellent intraclass correlation coefficients (ICCs) were obtained (ICC >0.87), except for internal primary coma (ICC = 0.75) and 3rd-order (ICC = 0.72) HOAs. Repeatability precision (1.96 × S(w)) values ranged from 0.03 μm (corneal primary spherical) to 0.08 μm (ocular primary coma). For intersession reproducibility (50 eyes), ICCs were good (>0.8) for ocular primary spherical, 3rd-order, and total higher-order aberrations; reproducibility precision values ranged from 0.06 μm (corneal primary spherical) to 0.21 μm (internal 3rd order), with internal HOAs having the lowest precision (≥0.12 μm). No systematic bias was found between examinations on different days. CONCLUSIONS: The intrasession repeatability was high; therefore, the device's ability to measure HOAs in a reliable way was excellent. Under intersession reproducibility conditions, dependable corneal primary spherical aberrations were provided. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
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