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  • Title: Infections after orthotopic liver transplantation in the intensive care unit.
    Author: Karapanagiotou A, Kydona C, Papadopoulos S, Giasnetsova T, Sgourou K, Pasakiotou M, Fouzas I, Papanikolaou V, Gritsi-Gerogianni N.
    Journal: Transplant Proc; 2012 Nov; 44(9):2748-50. PubMed ID: 23146512.
    Abstract:
    PURPOSE: The purpose of the study was to assess the characteristics and risk factors of infections in the early period after orthopic liver transplantation (OLT) among adult patients. MATERIAL AND METHODS: We studied 75 patients who underwent OLT over 3 years from 2008 to 2010. We recorded all infections that developed during hospitalization in the intensive care unit (ICU) their outcomes, and the possible risk factors. RESULTS: During the study period in 80 OLT we recorded 19 bloodstream infections (47.5%), 7 ventilator-associated pneumonias (VAP; 17.5%), and 14 intra-abdominal infections (35%). Among the 40 isolated microbes, 72.5% were Gram negative, 25% were Gram positive, and 2.5% were fungi. The median time to developing the infection was 4.95 days (range 2-10). Patients with infections showed longer durations of mechanical ventilation, longer lengths of ICU stay, and lower 1-year survivals.
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