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  • Title: Two new compounds from Hicriopteris glauca and their potential antitumor activities.
    Author: Fang X, Lin X, Liang S, Zhang WD, Feng Y, Ruan KF.
    Journal: J Asian Nat Prod Res; 2012; 14(12):1175-9. PubMed ID: 23157308.
    Abstract:
    Chemical examination of the EtOAc extract from the stems of Hicriopteris glauca (Thunb) Ching. led to the isolation of two new compounds: lunularic acid 4'-glucoside and 2,9-dihydroxy-4,7-megastigmadiene-3-O-β-glucoside. Their structures were elucidated on the basis of spectral analysis and by comparing their spectral data with those in literature. Two compounds, along with the petroleum ether, chloroform, EtOAc, and n-BuOH extracts, were tested for cytotoxic activities. Only the n-BuOH extract showed antitumor activity against human melanoma A375 cells with IC₅₀ values of 0.80 μg/ml.
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