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  • Title: Dilutional acidosis.
    Author: Goodkin DA, Raja RM, Saven A.
    Journal: South Med J; 1990 Mar; 83(3):354-5. PubMed ID: 2315790.
    Abstract:
    Rapid, extreme expansion of the extracellular fluid with solutions devoid of acid or alkali theoretically can produce a metabolic acidosis, due to buffer dilution. This phenomenon has previously been demonstrated only in experimental animal studies. We have reported what we believe to be the first documented case of hypobicarbonatemia and metabolic acidosis consequent to massive saline infusion, other causes having been excluded.
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