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  • Title: Cervical cancer cell lines containing herpesvirus markers.
    Author: Melnick JL, Adam E, Lewis R, Kaufman RH.
    Journal: Intervirology; 1979; 12(2):111-4. PubMed ID: 231583.
    Abstract:
    Five epithelioid cell lines were established from invasive cervical carcinoma tissue and were examined for herpes simplex virus (HSV) antigens or virus-induced changes. Immunofluorescence studies with antiserum to an HSV type 2 nonstructural polypeptide detected perinuclear antigens. In these cell lines, concentrations of a membrane fucopeptide that is regularly present in normal cells were reduced to levels similar to those previously observed in virus-transformed cells. One of the cell lines inoculated into athymic mice produced tumors.
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