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  • Title: Effect of low direct current on anaerobic multispecies biofilm adhering to a titanium implant surface.
    Author: Sahrmann P, Zehnder M, Mohn D, Meier A, Imfeld T, Thurnheer T.
    Journal: Clin Implant Dent Relat Res; 2014 Aug; 16(4):552-6. PubMed ID: 23167678.
    Abstract:
    PURPOSE: Peri-implantitis is caused by biofilm adhering to the implant. It has been shown that bactericidal electrolysis products are generated when a low direct current is applied to a titanium implant used as the anode. The hypothesis of this study was that low-current electrolysis would eradicate viable bacteria in a simulated subgingival multispecies biofilm adhering to a titanium implant surface. MATERIAL AND METHODS: Biofilms consisting of eight anaerobic species were grown on pellicle-coated titanium discs with sand-blasted, acid-etched, large-grit (SLA; Straumann, Basel, Switzerland) surface. After 40.5 hours of growth, discs were treated with 10 mA for 10 minutes in an electrolytical setup with physiological saline and gelatin. RESULTS: Low direct current at discs used as the cathode caused a reduction of three to four orders of magnitude in viable counts, while no viable bacteria were recovered from anode discs (Mann-Whitney U-test, p < .01). Confocal laser scanning microscopy in combination with a live/dead stain showed biofilm detachment at the cathode and reduced viability at the anode. CONCLUSION: Electrochemical treatment of diseased implants appears to be promising and well worth investigating further.
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