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  • Title: In vivo blood T(1) measurements at 1.5 T, 3 T, and 7 T.
    Author: Zhang X, Petersen ET, Ghariq E, De Vis JB, Webb AG, Teeuwisse WM, Hendrikse J, van Osch MJ.
    Journal: Magn Reson Med; 2013 Oct; 70(4):1082-6. PubMed ID: 23172845.
    Abstract:
    The longitudinal relaxation time of blood is a crucial parameter for quantification of cerebral blood flow by arterial spin labeling and is one of the main determinants of the signal-to-noise ratio of the resulting perfusion maps. Whereas at low and medium magnetic field strengths (B0), its in vivo value is well established; at ultra-high field, this is still uncertain. In this study, longitudinal relaxation time of blood in the sagittal sinus was measured at 1.5 T, 3 T, and 7 T. A nonselective inversion pulse preceding a Look-Locker echo planar imaging sequence was performed to obtain the inversion recovery curve of venous blood. The results showed that longitudinal relaxation time of blood at 7 T was ∼ 2.1 s which translates to an anticipated 33% gain in the signal-to-noise ratio in arterial spin labeling experiments due to T1 relaxation alone compared with 3 T. In addition, the linear relationship between longitudinal relaxation time of blood and B0 was confirmed.
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