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  • Title: Extramedullary plasmacytomas and solitary plasma cell tumours of bone.
    Author: Brinch L, Hannisdal E, Abrahamsen AF, Kvaløy S, Langholm R.
    Journal: Eur J Haematol; 1990 Feb; 44(2):132-5. PubMed ID: 2318296.
    Abstract:
    We describe clinical features and treatment results in 25 patients with solitary osseous (SOP) and 18 patients with solitary extramedullary plasmacytoma (EMP). 41 patients were treated with high-voltage radiotherapy, median 40 Gy in 20 fractions. Surgery was part of the treatment in 21 and chemotherapy in 5 patients. The median age in both groups was 56 years, with a preponderance of males. Myelomatosis developed in 10 SOP and 2 EMP patients, and this development did not correlate with the presence or absence of an M-component at the time of diagnosis of plasmacytoma. The estimated 5- and 10-y survival was 87% and 76% without a statistical difference between SOP and EMP groups. The patients in the SOP group usually died from myelomatosis while EMP patients died from other causes.
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