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  • Title: Chronic renal failure complications and management in kidney transplanted and nontransplanted patients.
    Author: Kaysi S, Hadj Abdelkader M, Aniort J, Garrouste C, Philipponnet C, Deteix P, Heng AE.
    Journal: Transplant Proc; 2012 Dec; 44(10):2997-3000. PubMed ID: 23195013.
    Abstract:
    BACKGROUND: Our purpose was to compare the management of chronic kidney disease (CKD) according to Kidney Disease Quality Initiative (K/DOQI) recommendations in kidney transplanted patients (T) and nontransplanted ones (NT). METHODS: Data concerning CKD complications were collected retrospectively. Patients seen in consultations in our department from May 2009 to June 2010 were selected if they had at least 6 months of follow-up, CKD stage 4 or 5, and no exclusion criteria namely hospitalization, active cancer, or infection in the 3 months before data collection. RESULTS: Fifty-eight T were compared with 85 NT matched by CKD stage (4-5). Anemia within K/DOQI target was better controlled among NT (51.2% versus 41.3%); however, ferritin levels within K/DOQI target were higher (80% T versus 51.7% NT). Average arterial blood pressure was similar in both groups but 51.7% of T were in K/DOQI target versus 41% of NT. Dyslipidemia within cholesterol K/DOQI target was better controlled in 60% (NT) versus 35% NT with 63.5% versus 38% NT within low-density lipoprotein K/DOQI targets. Phosphorus level was better controlled among T; parathyroid was better controlled in among 65% NT versus 50% T within the target level. CONCLUSION: Most complications of CKD were better managed among NT.
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