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  • Title: Early alterations of cochlear function in experimental perilymph fistulas.
    Author: Böhmer A.
    Journal: Laryngoscope; 1990 Apr; 100(4):389-94. PubMed ID: 2319888.
    Abstract:
    Alterations of cochlear function secondary to perforation of the round window membrane in guinea pigs were expected to reveal sensitive and/or specific audiometric parameters in perilymph fistulas. A perforation of the round window membrane either did not affect acoustic compound action potential thresholds, or induced a delayed, possibly conductive, inner ear hearing loss. Also, evoked suprathreshold responses deteriorated progressively and independently of the increase of compound action potential thresholds. A sudden (conductive) hearing loss and a poor response to suprathreshold stimulation might indicate inner ear damage secondary to a perilymphatic fistula.
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