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  • Title: Action of retinoids during transformation of 10T1/2 cells.
    Author: Przybyszewska M, Janik P, Miłoszewska J, Szaniawska B.
    Journal: Neoplasma; 1990; 37(1):37-41. PubMed ID: 2320179.
    Abstract:
    The effect of three retinoids, 13-cis-retinoic acid, arotinoid ethyl sulfone and retinal acetate, on methylcholanthrene (MCA) induced transformation of 10T1/2 cells was studied. It appears that 13-cis-retinoic acid and arotinoid ethyl sulfone prevent transformation in a direct way at the last stage of carcinogenesis. Retinal acetate, however, requires cell-to-cell contacts to inhibit the transformation of 10T1/2 cells.
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