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  • Title: Effect of soy isoflavone supplementation on menopausal quality of life.
    Author: Amato P, Young RL, Steinberg FM, Murray MJ, Lewis RD, Cramer MA, Barnes S, Ellis KJ, Shypailo RJ, Fraley JK, Konzelmann KL, Fischer JG, LaSalle C, Smith EO, Wong WW.
    Journal: Menopause; 2013 Apr; 20(4):443-7. PubMed ID: 23211877.
    Abstract:
    OBJECTIVE: The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. METHODS: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. RESULTS: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. CONCLUSIONS: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.
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