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  • Title: Carbon catabolite regulation of phenylacetyl-CoA ligase from Pseudomonas putida.
    Author: Martinez-Blanco H, Reglero A, Luengo JM.
    Journal: Biochem Biophys Res Commun; 1990 Mar 30; 167(3):891-7. PubMed ID: 2322284.
    Abstract:
    Phenylacetyl-CoA ligase (PA-CoA ligase) from P. putida U is a newly described enzyme involved in the aerobic catabolism of phenylacetic acid. The enzyme was specifically induced when P. putida was grown in a chemically defined medium containing phenylacetic acid as the sole carbon source. The induction of PA-CoA ligase was delayed by adding easily metabolizable carbon sources to the medium; the effect was more drastic in the presence of glucose. Glucose did not cause catabolic inactivation but rather catabolic repression, this effect being reversed by cAMP.
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