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  • Title: How many sputum culture results do we need to monitor multidrug-resistant-tuberculosis (MDR-TB) patients during treatment?
    Author: Janssen S, Padanilam X, Louw R, Mahanyele R, Coetzee G, Hänscheid T, Leenstra T, Grobusch MP.
    Journal: J Clin Microbiol; 2013 Feb; 51(2):644-6. PubMed ID: 23224098.
    Abstract:
    Discharge of a hospital patient after a single negative sputum culture may save money when treating multidrug-resistant tuberculosis. However, after initial sputum conversion in 336 South Africans, 11.6% and 5.4% reconverted after 1 and 2 months, respectively. These findings endorse the WHO definitions of 2 negative cultures taken ≥ 30 days apart after sputum culture conversion.
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