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  • Title: Duodenal gastrointestinal stromal tumors (GISTs): arguments for conservative surgery.
    Author: Bourgouin S, Hornez E, Guiramand J, Barbier L, Delpero JR, Le Treut YP, Moutardier V.
    Journal: J Gastrointest Surg; 2013 Mar; 17(3):482-7. PubMed ID: 23229887.
    Abstract:
    INTRODUCTION: Gastrointestinal stromal tumors (GISTs) of the duodenum are rare. We sought to evaluate the postoperative courses and long-term outcomes of conservative surgery (CS) versus pancreaticoduodenectomy (PD) for patients with non-metastatic duodenal GISTs. METHODS: Seventeen patients underwent surgery for duodenal GISTs between January 2000 and January 2012; 11 patients underwent CS (CS group), and six patients underwent a PD (PD group). RESULTS: Mortality was similar between the two groups. Patients in the PD group had longer operative times, more tumors located on the pancreatic side of the duodenum, higher rates of post-operative complications including postoperative pancreatic fistulas, and a longer hospital stay, when compared with patients of CS group. All tumors were resected with clear surgical margins (R0 resection). The median disease-free survival times were not different. CONCLUSION: CS was safe and provided similar oncologic outcomes as PD. CS should be the procedure of choice in patients with GIST that does not involve the pancreatic side of the duodenum.
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