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  • Title: The common fragile site in band q27 of the human X chromosome is not coincident with the fragile X.
    Author: Sutherland GR, Baker E.
    Journal: Clin Genet; 1990 Mar; 37(3):167-72. PubMed ID: 2323087.
    Abstract:
    The common fragile site on the end of the long arm of the human X chromosome has been shown to be at a different location from the rare fragile site which produces the fragile X syndrome of intellectual handicap. The different locations can be clearly seen in chromosomes at about the 550 band level of resolution. This finding should help resolve difficulties in fragile X cytogenetics where expression of the common fragile site can lead to false positive diagnoses.
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