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  • Title: Bilateral mediastinal neurofibroma of the vagus nerves in a patient with neurofibromatosis type 1.
    Author: Kanzaki R, Inoue M, Minami M, Sawabata N, Shintani Y, Nakagiri T, Okumura M.
    Journal: Ann Thorac Cardiovasc Surg; 2013; 19(4):293-6. PubMed ID: 23232267.
    Abstract:
    Bilateral mediastinal vagus neurogenic tumors are very rare. We herein report the case of Neurofibromatosis type 1 (NF-1) patient with bilateral neurofibromas originating from the mediastinal vagus just distal site of the recurrent nerve, who underwent two-staged extirpations that successfully preserved both recurrent nerves. A 31-year-old female with a history of NF-1 was admitted to our hospital under a diagnosis of multiple tumors in the upper mediastinum. First, the tumor at the right paratracheal to precarinal site was completely resected through a median sternotomy, preserving the right recurrent nerve. After confirming no right recurrent nerve paralysis, thoracoscopic resection of the tumor at the aorto-pulmonary window was then performed preserving the left recurrent nerve. The histopathological diagnosis was neurofibroma originating from the bilateral mediastinal vagus nerves. A two-staged operation can be an option in cases with bilateral mediastinal vagus nerve tumors to avoid the risk of bilateral recurrent nerve paralysis.
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