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  • Title: [Lipids in the lungs and alveolar surfactant in anaphylactic shock].
    Author: Bashmakov IuK, Briuzgina TS.
    Journal: Fiziol Zh (1978); 1990; 36(1):87-90. PubMed ID: 2323452.
    Abstract:
    The process of anaphylactoid response of rats to introduction of egg protein is associated with a decrease of the pulmonary surfactant surface activity. The factors of metabolic surfactant inactivation are as follows: protein accumulation, the disturbance of lipids transport between pulmonary cells and alveolar surface, change in fatty-acidic composition of surfactant phospholipids. The isolation of arachidonic acid from surfactant phospholipids in anaphylactoid shock is an evidence for the participation of the pulmonary surface-active phase in the process of biosynthesis of the lipid mediators in respiratory organs.
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