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  • Title: A comparison of patterns of disease extension in keratosis obturans and external auditory canal cholesteatoma.
    Author: Shinnabe A, Hara M, Hasegawa M, Matsuzawa S, Kanazawa H, Yoshida N, Iino Y.
    Journal: Otol Neurotol; 2013 Jan; 34(1):91-4. PubMed ID: 23235551.
    Abstract:
    OBJECTIVE: To investigate the different pathways of progression to the middle ear in keratosis obturans (KO) and external auditory canal cholesteatoma (EACC). STUDY DESIGN: Retrospective case review. SETTING: Referral hospital otolaryngology department. PATIENTS: Patients with KO or EACC and middle ear disease who underwent surgical management were included. Four ears of 4 patients (mean age, 41.25 yr) were the KO group, and 5 ears of 4 patients (mean age, 49.5 yr) were the EACC group. MAIN OUTCOME MEASURES: Intraoperative findings of the middle ear cavity were investigated in KO and EACC groups. RESULTS: In the KO group, 3 patients had a perforated tympanic membrane and cholesteatoma in the tympanic cavity. The other patient had preoperative right facial palsy. Removal of the keratin plug revealed an adherent tympanic membrane. In intraoperative findings, the tympanic segment of the fallopian canal was found to be eroded because of inflammation. No case initially progressed to the mastoid cavity. Four patients had external auditory canal cholesteatoma with middle ear disease. In EACC group, all patients had initial progression to the mastoid cavity. CONCLUSION: KO tends to progress initially to the tympanic cavity via a diseased tympanic membrane. EACC tends to progress to the mastoid cavity via destruction of the posterior bony canal. This is the first report to investigate differences in pathway of progression to the middle ear cavity in these 2 diseases.
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