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  • Title: Infantile pyknocytosis: an under-recognized form of neonatal hemolytic anemia?
    Author: Coutinho M, Costa E, Monteiro T, Silva G, Costa H, Guedes A, Freitas I, Barbot J.
    Journal: Lab Hematol; 2012 Dec; 18(4):27-9. PubMed ID: 23253864.
    Abstract:
    Infantile pyknocytosis (IP) is an under-recognized hematological entity of newborns that can cause a severe neonatal hemolytic anemia. A careful, prompt, and accurate peripheral blood smear examination is essential to establish the diagnosis. Here we describe the clinical features and histological parameters of 1 case of IP. Spontaneous resolution usually occurs by 4 to 6 months, but red blood cell transfusion may be needed if the anemia is severe.
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