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  • Title: Palladium-catalyzed Saegusa-Ito oxidation: synthesis of α,β-unsaturated carbonyl compounds from trimethylsilyl enol ethers.
    Author: Lu Y, Nguyen PL, Lévaray N, Lebel H.
    Journal: J Org Chem; 2013 Jan 18; 78(2):776-9. PubMed ID: 23256839.
    Abstract:
    Palladium-catalyzed Saegusa-Ito oxidation of trimethylsilyl enol ethers is possible using Oxone as a stoichiometric oxidant and sodium hydrogen phosphate as a buffer. Cyclic and acyclic enones as well as α,β-unsaturated aldehydes are obtained in good to excellent yields.
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