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  • Title: [Sleep stages and growth hormone in manganese poisoning. Effects of L dopa].
    Author: Aranda L, López G, Horiuchi K, Mena I, Court J.
    Journal: Acta Neurol Latinoam; 1976; 22(1-4):42-9. PubMed ID: 232604.
    Abstract:
    Sleep characteristics are studied in 7 patients with sequelae of manganese intoxication and in 8 controls. A reduction in the length of the REM stage was observed, which could be prolonged by L Dopa administration, but without achieving values comparable to the controls. No changes were noted in the non-REM stage of sleep. These results are similar to the ones obtained in Parkinson's disease, suggesting clinical and probably biochemical similarities between the 2 conditions. The blood concentrations of growth hormone during sleep in the manganic patients was lower than in the control group, and no significant variations were noted after L Dopa administration.
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