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  • Title: Treatment discontinuation in couples consulting for male infertility after failing to conceive.
    Author: Walschaerts M, Bujan L, Parinaud J, Mieusset R, Thonneau P.
    Journal: Fertil Steril; 2013 Apr; 99(5):1319-23. PubMed ID: 23260858.
    Abstract:
    OBJECTIVE: To evaluate rates and reasons for treatment discontinuation in couples with male factor infertility and who failed to conceive. DESIGN: Retrospective study. SETTING: Male Sterility Center, University Hospital. PATIENT(S): A total of 407 couples consulting for male factor infertility and who discontinued treatment without conceiving. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Treatment, reasons for dropout, and reproductive outcomes after discontinuation. RESULT(S): Of the 407 patients, 218 (54%) had had fertility treatment (medical or surgical), and 189 (46%) underwent assisted reproductive techniques (ART) (intrauterine insemination [IUI], in vitro fertilization [IVF], or intracytoplasmic sperm injection [ICSI]). The main reasons for dropout were painfulness of treatment (15% for patients with non-ART treatment vs. 32% for patients who had undergone ART), its ineffectiveness (12% vs. 26%), and separation of the couple (18% vs. 7%). Of the 407 patients, 27% consulted in another fertility center, 8% succeeded in having a child by ART with male partner sperm, 1% by ART with donor sperm, and 11% through adoption. CONCLUSION(S): About half of the couples consulting for male factor infertility discontinued fertility treatment, and of those who discontinued only a fifth finally succeeded in having a child. Although support is available to couples during fertility care, ART is a physical and psychological burden.
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