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  • Title: [Two cases of complete response for cStage I( T1bN0M0) esophageal carcinoma treated with chemoradiation therapy].
    Author: Nishigaki T, Okada K, Ebisui C, Wada Y, Kato R, Makino S, Owada Y, Murakami M, Yanagisawa T, Okamura S, Murata K, Yokouchi H, Kinuta M.
    Journal: Gan To Kagaku Ryoho; 2012 Nov; 39(12):2107-9. PubMed ID: 23267992.
    Abstract:
    We report 2 cases of complete response for cStage I(T1bN0M0) esophageal carcinoma treated with chemoradiation therapy. Case 1: A 70-year-old man was diagnosed with cStage I(T1bN0M0) thoracic esophageal carcinoma(Type 0- IIc, squamous cell carcinoma). efinitive chemoradiotherapy (5-FU 250 mg/m2, CDDP 5 mg/m2 days 1-5, 8-12, 15-19, 22-26, 29-33, and 36-40; radiation: 60 Gy/30 Fr) was administrated. After treatment, we confirmed that the esophageal lesion had disappeared by upper endoscopy. Case 2: A 78-year-old man was diagnosed with cStage I(T1bN0M0) thoracic esophageal carcinoma (Type 0-I+IIb, squamous cell carcinoma) and early stage gastric carcinoma. Considering his general condition, radical surgery for esophageal cancer and gastric cancer was difficult; hence, he was treated with definitive chemoradiotherapy. After treatment, the esophageal lesion disappeared and we performed fundusectomy. Chemoradiation therapy appears to be effective for patients with cStage I(T1bN0M0) esophageal carcinoma.
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