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  • Title: New sesquiterpenes and phenolic compound from Ficus foveolata.
    Author: Somwong P, Suttisri R, Buakeaw A.
    Journal: Fitoterapia; 2013 Mar; 85():1-7. PubMed ID: 23274776.
    Abstract:
    Two new eudesmane-type sesquiterpenes, named foveolide A (1) and foveoeudesmenone (2), one new sesquiterpenoid dimer, foveolide B (3) and a new phenolic compound, foveospirolide (4), were isolated along with six known compounds, including 4(15)-eudesmene-1β, 6α-diol (5), 4(15)-eudesmene-1β, 5α-diol (6), friedelin, taraxerol, betulin and ethyl rosmarinate, from the stems of Ficus foveolata. The structures of these new compounds were characterized by spectroscopic methods (IR, MS and NMR). Compound 1 exhibited moderate cytotoxicity against SW620, HepG2, BT474 and KATO-III cancer cell lines, whereas compound 3 was specifically cytotoxic toward SW620 cell line.
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